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Muscle Growth Peptides

Muscle growth peptides work through IGF-1 signaling, satellite cell activation, and growth hormone axis stimulation. IGF-1 LR3 directly activates anabolic pathways in muscle tissue. Follistatin-344 in...

Overview

Muscle growth peptides work through IGF-1 signaling, satellite cell activation, and growth hormone axis stimulation. IGF-1 LR3 directly activates anabolic pathways in muscle tissue. Follistatin-344 inhibits myostatin — the protein that limits muscle growth. GH secretagogues enhance the endogenous anabolic hormone environment. These are among the most researched compounds for body recomposition.

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IGF-1 LR3

Insulin-like Growth Factor 1 Long R3

Mechanism

Long-acting analogue of IGF-1. Directly activates IGF-1 receptors in muscle tissue, promoting satellite cell differentiation (muscle stem cells) and protein synthesis. 3x longer half-life than regular IGF-1.

Benefits

  • Satellite cell activation (permanent muscle fiber increase)
  • Enhanced nutrient partitioning
  • Direct anabolic effect independent of GH
  • Recovery enhancement
  • Anti-catabolic

Dosing

10–20mcg per day SubQ or IM near trained muscle. Start at 10mcg.

Reconstitution

1mg + 3mL BAC = 333mcg/mL. Draw 3 units for 10mcg, 6 units for 20mcg.

Cycle Length

4–6 weeks on, 4–6 weeks off. IGF-1 receptor downregulation occurs with prolonged use.

Timing

Post-workout on training days, or morning on non-training days.

Stacks Well With

Ipamorelin/CJC-1295, BPC-157 (injury protection during aggressive training)

Cautions

Hypoglycemia possible — have food available after injection. Avoid with cancer history (powerful mitogen). Start very low (10mcg).

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Follistatin-344

FST-344

Mechanism

Glycoprotein that inhibits myostatin and activin — proteins that limit muscle growth. Essentially removes the brake on muscle development.

Benefits

  • Myostatin inhibition
  • Enhanced muscle fiber growth potential
  • Improved recovery
  • Complementary to anabolic peptides

Dosing

100mcg/day × 10 days. Often cycled in short bursts.

Reconstitution

Varies by supplier. Typically 1mg vial. Consult supplier for BAC water amount.

Cycle Length

10-day cycles, 2–3 times per year.

Timing

Daily SubQ during cycle.

Stacks Well With

IGF-1 LR3, GH secretagogues

Cautions

Limited human research. Cancer concern (cell proliferation). Avoid with cancer history.

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Frequently Asked Questions