Peptide Injection Guide
Most peptides are injected subcutaneously (SubQ) — into the fat layer just beneath the skin. It's simpler, less painful, and equally effective for most compounds.
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Needle Selection
SubQ (subcutaneous — into fat layer):
• 31 gauge × 8mm (5/16") insulin needle — ideal for belly/love handles
• 31 gauge × 6mm — for leaner individuals
• 1mL/100-unit insulin syringe
IM (intramuscular — into muscle):
• 25 gauge × 1" — glutes
• 27 gauge × 0.5" — delts, quads
• Not needed for most peptides unless specifically indicated (Thymalin, NAD+ IM)
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SubQ Injection Technique
Step 1: Wash hands. Wipe injection site with alcohol swab. Let dry 30 seconds.
Step 2: Pinch 1-2 inches of fat between thumb and index finger (belly fat, love handles, or upper thigh).
Step 3: Insert needle at 45–90 degrees depending on site. 45° for lean individuals, 90° for more fat.
Step 4: Release the pinch (don't inject into a pinched fold).
Step 5: Inject slowly and steadily. Don't rush.
Step 6: Remove needle and apply gentle pressure with alcohol swab. Don't rub.
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Injection Sites and Rotation
Primary SubQ sites:
• Lower abdomen (2 inches from navel) — most common
• Love handles / flanks
• Upper thigh
• Upper outer arm
Rotation rule: Move at least 1-2cm from previous injection. Keep a mental map or written log. Repeated injection in the same spot causes:
• Lipodystrophy (fat tissue damage)
• Scar tissue
• Reduced absorption
• Lumps
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Dealing With Injection Pain
Some peptides sting more than others:
• GHK-Cu: stings significantly — hyperdilute with more BAC water (5–10mL)
• LL-37: can cause notable site pain — ice before injection helps
• NAD+: burn if injected too fast — inject slowly over 3–5 min per mL
• Most peptides: minimal discomfort with proper technique
Pre-injection ice for 60 seconds reduces sensation. Allow refrigerated peptides to warm to room temp before injecting.
Questions
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