Semaglutide
GLP-1 receptor agonist
GLP-1 receptor agonist. Slows gastric emptying, reduces appetite signaling in the hypothalamus, improves insulin sensitivity, and reduces glucagon secretion.
Dose
Start 250mcg/week
Cycle
Long-term
Timing
Once weekly SubQ injection
Benefits & Effects
- ✓15–20% body weight reduction (clinical trials)
- ✓Appetite suppression
- ✓Improved blood sugar control
- ✓Cardiovascular risk reduction
Reconstitution & Dosing
Reconstitution
5mg vial + 2mL BAC water = 2,500mcg/mL. 10mg vial + 2mL BAC = 5,000mcg/mL.
Dose
Start 250mcg/week. Increase by 250mcg every 4 weeks based on tolerance. Typical working dose: 1,000–2,500mcg/week.
Cycle Length
Long-term. Most researchers continue until goal weight, then taper.
Timing
Once weekly SubQ injection. Rotate sites (belly, thigh, upper arm).
Calculate Semaglutide dose
Auto-fills your vial size, BAC water, and desired dose. Gets your exact syringe units.
Stacking
Cagrilintide (additive effect), AOD-9604 (different mechanism)
Cautions
GI side effects common (nausea, vomiting) especially when titrating too fast. Pancreatitis risk (rare). Avoid if personal/family history of medullary thyroid cancer.
Frequently Asked Questions
What is Semaglutide used for?
Semaglutide is researched for: 15–20% body weight reduction (clinical trials), Appetite suppression, Improved blood sugar control, Cardiovascular risk reduction. GLP-1 receptor agonist. Slows gastric emptying, reduces appetite signaling in the hypothalamus, improves insulin sensitivity, and reduces glucagon secretion.
What is the standard dosing for Semaglutide?
Start 250mcg/week. Increase by 250mcg every 4 weeks based on tolerance. Typical working dose: 1,000–2,500mcg/week.
How do you reconstitute Semaglutide?
5mg vial + 2mL BAC water = 2,500mcg/mL. 10mg vial + 2mL BAC = 5,000mcg/mL. Store reconstituted peptide refrigerated at 2–8°C for up to 60–90 days.
What peptides stack well with Semaglutide?
Cagrilintide (additive effect), AOD-9604 (different mechanism)
Are there any cautions with Semaglutide?
GI side effects common (nausea, vomiting) especially when titrating too fast. Pancreatitis risk (rare). Avoid if personal/family history of medullary thyroid cancer.
What is the cycle length for Semaglutide?
Long-term. Most researchers continue until goal weight, then taper. Timing: Once weekly SubQ injection. Rotate sites (belly, thigh, upper arm).