Melanotan 1
MT-1, Afamelanotide, Scenesse
Selective MC1R agonist. Stimulates melanocytes to produce eumelanin (brown/black pigment). FDA-approved for EPP (erythropoietic protoporphyria).
Dose
250–500mcg daily or every other day
Cycle
Loading phase 2–4 weeks until desired color, then maintenance 1–2x/week
Timing
SubQ evening (nausea less noticeable during sleep)
Benefits & Effects
- ✓UV-independent tanning
- ✓Photoprotection
- ✓Approved for EPP
- ✓Minimal systemic effects vs MT-2
Reconstitution & Dosing
Reconstitution
10mg + 2mL BAC = 5,000mcg/mL.
Dose
250–500mcg daily or every other day. Start low (250mcg) to assess response.
Cycle Length
Loading phase 2–4 weeks until desired color, then maintenance 1–2x/week.
Timing
SubQ evening (nausea less noticeable during sleep).
Calculate Melanotan 1 dose
Auto-fills your vial size, BAC water, and desired dose. Gets your exact syringe units.
Stacking
N/A — typically used alone
Cautions
Causes darkening of existing moles — monitor for changes. Nausea during loading. Avoid if high-risk for melanoma.
Frequently Asked Questions
What is Melanotan 1 used for?
Melanotan 1 is researched for: UV-independent tanning, Photoprotection, Approved for EPP, Minimal systemic effects vs MT-2. Selective MC1R agonist. Stimulates melanocytes to produce eumelanin (brown/black pigment). FDA-approved for EPP (erythropoietic protoporphyria).
What is the standard dosing for Melanotan 1?
250–500mcg daily or every other day. Start low (250mcg) to assess response.
How do you reconstitute Melanotan 1?
10mg + 2mL BAC = 5,000mcg/mL. Store reconstituted peptide refrigerated at 2–8°C for up to 60–90 days.
What peptides stack well with Melanotan 1?
N/A — typically used alone
Are there any cautions with Melanotan 1?
Causes darkening of existing moles — monitor for changes. Nausea during loading. Avoid if high-risk for melanoma.
What is the cycle length for Melanotan 1?
Loading phase 2–4 weeks until desired color, then maintenance 1–2x/week. Timing: SubQ evening (nausea less noticeable during sleep).